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THE PICOWER INSTITUTE

Massachusetts Institute of Technology
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Cambridge, MA 02139
(+1) 617-324-0305
(+1) 617-452-2588

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You searched for: TRAP

NIH award to help Heiman unearth roots of Huntington’s pathology

Thursday, May 26
… early triggers of disease progression neurodegeneration TRAP Single Cell Transcriptomics and Epigenomics Research … In these younger mice the lab will use techniques such as TRAP to assess how DNA accessibility and gene transcription … Above: Spiny projection neurons labeled for analysis with TRAP technology. Image courtesy Heiman Lab. As they identify …
https://picower.mit.edu/node/923

Myriam Heiman

… Disease Neuro Genomics and Proteomics Parkinson's disease TRAP neurotechnology striatum CAG medium spiny neurons … termed Translating Ribosome Affinity Purification (TRAP). This methodology allows for the profiling of any … in any given cell at any given time. By combining the TRAP methodology with mouse models of Huntington’s disease …
https://picower.mit.edu/node/42

Neural vulnerability in Huntington’s disease tied to release of mitochondrial RNA

Friday, Jul 17
… neurons neuroimmunology Huntington's Disease aging mRNA TRAP striatum … mishap The team’s two different screening methods, “ TRAP ,” which can be used in mice, and single nucleus RNA …
https://picower.mit.edu/node/679

MIT biologists discover an unusual hallmark of aging in neurons

Tuesday, Nov 27
… in brain cells could interfere with normal function TRAP mRNA neuronal identity striatum prefrontal cortex …
https://picower.mit.edu/node/436

Special Seminar with Emily Osterweil, PhD, The University of Edinburgh

… we use a combination of CA1 pyramidal neuron-specific TRAP-seq and proteomics to identify the overtranslating mRNAs …
https://picower.mit.edu/node/922

'Risky' Research

Monday, Dec 20
… Huntington's Disease neuromodulation 40Hz oscillations TRAP fMRI How do bold, untested research projects get off the … or schizophrenia. She has, however, helped to develop TRAP, an innovative method for studying the unique patterns … and further funding from JPB , Heiman has been using TRAP to determine which cells antipsychotic drugs such as …
https://picower.mit.edu/node/873

Aging Brain Initiative

https://picower.mit.edu/node/25

Alumnus gives MIT $4.5 million to establish the Broderick Fund for Phytocannabinoid Research

Tuesday, Apr 30
… on cannabinoid’s influence on brain health and behavior TRAP oscillations attention working memory Charles R. …
https://picower.mit.edu/node/508

The story behind the science: How discovery develops

Thursday, Jun 25
… what was really happening.” The team didn’t fall into that trap because the experimental approach they chose didn’t …
https://picower.mit.edu/node/680

Massachusetts Institute of Technology
43 Vassar Street, Bldg. 46-1303
Cambridge, MA 02139
(+1) 617-324-0305
(+1) 617-452-2588

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From: http://picower.mit.edu/search