Wednesday, Jan 09
… disorder (BD) and shows how specific mutations in the SYNE1 gene that encodes the protein undermine its expression … are not suggesting that the CPG2-related variations in SYNE1 are “the cause” of bipolar disorder, but rather that … in brain circuits. When genetic studies identified SYNE1 as a risk gene specific to bipolar disorder, Nedivi’s …
Thursday, Feb 07
… bipolar disorder and showed how specific mutations in the SYNE1 gene that encodes CPG2 undermine the protein’s …
… synapse disassembly plasticity genes CPG15 Neuritin CPG2 SYNE1 visual system In vivo cellular imaging inhibitory …
Monday, Mar 14
… had reduced levels of CPG2 because of variations in the SYNE1 gene . When they cloned these variants into rats, they …
Monday, Dec 14
… showed how single and combinations of variants in the gene SYNE1 appear to undermine the ability to regulate synaptic … expression or function of CPG2, a key protein encoded by SYNE1, are sufficient to outright cause bipolar disorder on … going for you ? , ” Nedivi said. “ The constellation of SYNE1 variants in combination with the rest of your genetic …