Thursday, Feb 21
… will take on new questions of dementia neurodegeneration CRISPR/Cas9 organoids epigenetics In their collaboration to help … mini-brain organoids, tissue engineering, and CRISPR-Cas9 genetic manipulation. This allows their teams to …
Wednesday, Jul 31
… untreatable neurodevelopmental disorder Rett syndrome CRISPR/Cas9 stem cells neurodevelopmental disorders autism spectrum … to uncover drugs that increase KCC2 gene activity. Using CRISPR/Cas9 genome editing and stem cell technologies, they …
Tuesday, Aug 27
… New Research Sur lab will lead collaboration to create CRISPR, optogenetic innovations visual cortex motor cortex astrocytes astrocyte CRISPR/Cas9 In the brain, cells called astrocytes are at …
Thursday, May 31
… astrocytes, and microglia. Using the gene-editing system CRISPR/Cas9, the researchers genetically converted APOE3 in stem … that they could reverse most of these effects by using CRISPR/Cas9 to convert the APOE4 gene to APOE3 in brain cells …
… neuron. Using ex vivo electrophysiology, optogenetics, and CRISPR/Cas9 manipulations of Npas4, we find NPAS4 selectively …
… procedure for producing knock-out (KO) mice by ‘Triple-CRISPR’ method that targets a single gene by triple gRNAs in the CRISPR/Cas9 system achieves almost perfect KO efficiency (96%-100%). …
… role in Tau-mediated pathology. In addition, we are using CRISPR/Cas9-mediated genome editing to create calpain-resistant p35 … cells (iPSCs). We use genome-editing techniques such as CRISPR/Cas9 to create isogenic cell lines to facilitate the …
Monday, Dec 16
… same year, scientists demonstrated that a technique called CRISPR/Cas9, could be used for precise genetic editing. Scientists … scientists haven’t been sure why. Tsai and Lin’s team used CRISPR/Cas9 to make isogenic pairs of neurons, astrocytes and …
Thursday, Jan 30
… the disease’s toxic effects striatum Huntington's Disease CRISPR/Cas9 neurodegeneration … a particular gene’s information. Another makes use of CRISPR, a technique that can disrupt or delete specific genes …
Tuesday, Apr 21
… to viral entry to the brain. Using technologies like CRISPR/Cas9, the team can engineer such candidate risk genes into …
