June 08, 2020
Study finds path for addressing Alzheimer’s blood-brain barrier impairment
… About 25 percent of people have the APOE4 variant of the APOE gene, which puts them at substantially greater risk for … variant, pericytes in their vessels churn out too much APOE protein, explained senior author Li-Huei Tsai , Picower … of Neuroscience and director of the Picower Institute. APOE causes amyloid proteins, which are more abundant in …