March 10, 2023
3 questions for Mriganka Sur: The basic research origin of the first approved drug to treat Rett syndrome
… Rett syndrome was published by MIT in 2009. Rett syndrome plasticity IGF1 neurodevelopmental disorders MECP2 … that IGF-1 peptide increased expression of a number of synaptic molecules and made excitatory synapses stronger. … we could intervene to potentially offset the molecular and synaptic deficits and treat the disorder. This is the …

