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… cortex astrocytes astrocyte CRISPR/Cas9 In the brain, cells called astrocytes are at least as abundant as neurons, … – they haven’t been able to investigate many of the cells’ specific contributions because they have lacked the … run through July 2022. 46 147 30 33 240 13 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

… compound to correct gene expression in brain’s immune cells microglia neurodegeneration epigenetics Key studies … of gene expression in the brain’s innate immune cells, called microglia, may play a key role in the … the team’s grant proposal states. 2 8 240 Small Image in Place of Hero Off List on Aging Brain Initiative Page On List …

… the next stage is that we can use the function of these cells to overcome deficiencies,” Tonegawa said. The new depth … reactivating the engram of a previously experienced place while giving the mouse a little shock. Mice then exhibited a fearful response in that place, even though they hadn’t actually experienced the shock …

… decided to explore the role of sirtuins in endothelial cells, which line the inside of blood vessels. To do that, … which encodes the major mammalian sirtuin, in endothelial cells of mice. They found that at 6 months of age, these mice … and the National Institutes of Health. 33 Small Image in Place of Hero On List on Aging Brain Initiative Page On List …

… Science paper, Choi and Huh found that a type of immune cells known as Th17 cells, and their effector molecule, called IL-17, are … Autism Research. From MIT News 443 3 20 4 Small Image in Place of Hero Off List on news page On …

… Foundation to screen for genes that could help brain cells withstand Parkinson’s disease and to map how gene … disorder. The field knows little about what puts specific cells at such dire risk, or what molecular mechanisms might … of Parkinson’s disease.” 42 221 25 Small Image in Place of Hero Off List on Aging Brain Initiative Page On List …

… more fundamental understanding of the biology going on in cells of people with Down syndrome, often also called trisomy … in the lab is by engineering human cell cultures from cells taken from patients. Skin cells, for instance, can be … was real.” 2 147 10 12 8 25 279 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

… relationship between neurons and the brain cells called glia that help them function. Through four years … out the puzzle of exactly how the mutation made glial cells fail to prevent seizures was a source of particular … they could share with the world. 43 240 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …