… the same genome produced distinctions in form and function neuronalidentity Single Cell Transcriptomics and Epigenomics … for Learning and Memory found that the two closely related neuronal subtypes differed from each other in how they …
… genomic sites is lost, which contributes to loss of cell identity. The role of microglia In a third Cell paper, led by … of high cognitive function, dementia, and resilience to AD Neuronal DNA double-strand breaks lead to genome structural …
… How microglia alter brain infrastructures and influence neuronal activity Abstract: Microglia, traditionally … are involved in establishing and maintaining accurate neuronal circuit function in the retina and in the visual … strategies how to decipher the microglia’s functional identity and how this information guided us to microglia …
… and multi-patching electrophysiology, 3D reconstruction of neuronal morphology, and brain-wide connectivity mapping, to … and 5,322 clusters. We systematically analyzed the neuronal, non-neuronal, and immature neuronal cell types … a high degree of correspondence between transcriptomic identity and spatial specificity for each cell type. We also …
… of a gene called PTB. Data in mice show that after this “identity theft,” as Cleveland termed it, the newly converted … For instance, he’s found that the protein is necessary for neuronal hyperexcitability to emerge in Alzheimer’s disease …
