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THE PICOWER INSTITUTE

Massachusetts Institute of Technology
43 Vassar Street, Bldg. 46-1303
Cambridge, MA 02139
(+1) 617-324-0305
(+1) 617-452-2588

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BRAIN grant will fund new tools to study astrocytes

August 27, 2019
… astrocytes labeled blue also show green staining for calcium and red staining for ChromeQ a new tool for … the team will target different genes related to calcium biochemistry. One tool will give them temporal … control over receptors that the cells use to regulate calcium levels around neurons, for instance to intentionally …

New tool offers snapshots of neuron activity

June 26, 2017
… moment.” The researchers designed their tool to respond to calcium, because neurons experience an flux of calcium ions every time they fire an electrical impulse. However, the neurons are only labeled if this calcium flux occurs while the cell is also exposed to a beam …

Study connects neural gene expression differences to functional distinctions

August 23, 2023

With new grant, MIT neuroscientists will give 'invisible' cells a new look

February 08, 2018
… astrocytes do signal their activity with increases of calcium. A decade ago in Science , Sur and colleagues used … formation of neural connections called synapses, how the calcium activity arises, and what difference that activity … have their spiking code, we think there is an astrocyte calcium code that reflects and works in partnership with …

‘Researching from Home’: Picower science stays strong even at a distance

April 01, 2020

Young Picower scientists present projects at ‘SfN’

November 12, 2021
… to ourselves?” Above: Wilson lab postdoc Wei Guo, employed calcium imaging of neural activity to show that over the …

Study finds ‘volume dial’ for turning neural communication up or down

May 06, 2020
… of neurotransmitters when triggered by an influx of calcium ions. But even with SYT1 disabled, synapses could … SYT7 they didn’t see major differences in anatomy or calcium influx that could explain how SYT7 works to limit …

Feast or forage: Study finds circuit that helps a brain decide

November 22, 2021
… To keep constant track of neural activity, as indicated by calcium-triggered flashes of light, the Flavell lab invented … of neurons across the worm’s brain, as indicated by calcium-triggered flashes of light. Ji used the scope to …

Study of synapse strength focuses on ‘active zones’

March 16, 2021

Live imaging method brings structural information to mapping of brain function

September 17, 2020
… when they become electrically active (and show changes in calcium) in response to a particular stimulation. For …

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Massachusetts Institute of Technology
43 Vassar Street, Bldg. 46-1303
Cambridge, MA 02139
(+1) 617-324-0305
(+1) 617-452-2588

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From: https://picower.mit.edu/search