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… compound to correct gene expression in brain’s immune cells microglia neurodegeneration epigenetics Key studies … of gene expression in the brain’s innate immune cells, called microglia, may play a key role in the … the team’s grant proposal states. 2 8 240 Small Image in Place of Hero Off List on Aging Brain Initiative Page On List …

… the next stage is that we can use the function of these cells to overcome deficiencies,” Tonegawa said. The new depth … reactivating the engram of a previously experienced place while giving the mouse a little shock. Mice then exhibited a fearful response in that place, even though they hadn’t actually experienced the shock …

… decided to explore the role of sirtuins in endothelial cells, which line the inside of blood vessels. To do that, … which encodes the major mammalian sirtuin, in endothelial cells of mice. They found that at 6 months of age, these mice … and the National Institutes of Health. 33 Small Image in Place of Hero On List on Aging Brain Initiative Page On List …

… while the LS dedicates a much smaller proportion of its cells to encoding location than does the hippocampus, a much … work that shows somewhat overlapping populations of place-encoding and movement-encoding LS cells,” Wirtshafter … funding for the study. 49 15 22 20 14 24 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

… Science paper, Choi and Huh found that a type of immune cells known as Th17 cells, and their effector molecule, called IL-17, are … Autism Research. From MIT News 443 3 20 4 Small Image in Place of Hero Off List on news page On …

… widespread and debilitating death of nervous system cells, but they also share other grim characteristics: Their … which envelop the brain, becomes a means for immune cells activated by gut bacteria to circulate near the brain … to the Aging Brain Initiative Fund . 443 8 Small Image in Place of Hero On List on Aging Brain Initiative Page On List …

… more fundamental understanding of the biology going on in cells of people with Down syndrome, often also called trisomy … in the lab is by engineering human cell cultures from cells taken from patients. Skin cells, for instance, can be … was real.” 2 147 10 12 8 25 279 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

… brain-on-a-chip model of Alzheimer’s disease. stem cells organoids Alzheimer's dementia neurodegeneration … who helped me get to this point.” 2 8 222 Small Image in Place of Hero On List on Aging Brain Initiative Page Off List …