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… release chemicals that are usually associated with energy metabolism to signal neurons to alter their activity. “So … express genes associated with antioxidant activity and metabolism of the nutrient choline, that helps protect the …

… for any cell to survive, such as enzymes involved in cell metabolism or copying DNA into RNA. The findings also …

… neurodegeneration microglia astrocytes amyloid beta lipid metabolism … version of the APOE gene, which is normally involved in metabolism and transport of fatty molecules such as … APOE4 astrocytes, the researchers found that cholesterol metabolism was highly dysregulated. The cells produced twice …

… of ApoE, and the increasingly recognized role of lipid metabolism in Alzheimer’s disease.  "Unearthing these … DEGs associated with AD are linked to lipid/cholesterol metabolism, to AD genetic risk factors (including ApoE) and …

… mechanism: ferroptosis. This phenomenon, in which errant metabolism of iron leads to a lethal buildup of reactive …