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… Disorder Neuroimmune interactions anesthesia amygdala CPG2 Neuromodulators Picower Institute studies reveal a … Elly Nedivi's lab has linked low levels of the protein CPG2 to increased risk of bipolar disorder. Here they've … with bipolar disorder had lower levels in the brain of the CPG2 protein, a product of the SYNE1 gene which had been …

… and synaptic function of two previously unknown CPGs: CPG2 and CPG15. In a study published earlier this year, her lab showed that the protein CPG2 is significantly less abundant in the brains of people … how specific mutations in the SYNE1 gene that encodes CPG2 undermine the protein’s expression and its function in …

… candidate plasticity genes Bipolar Disorder IGF1 mGluR5 CPG2 DNA’s resemblance to a twisted ladder provides an apt … of these variants which affect expression or function of CPG2, a key protein encoded by SYNE1, are sufficient to … you will develop the disease .”   Nedivi ’s lab discovered CPG2 while screening neurons for proteins whose expression …