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… Study models how ketamine’s molecular action leads to its effects on the brain … Findings New research addresses a gap in understanding how ketamine’s impact on individual neurons leads to pervasive … changes in brain network function. depression anesthesia ketamine Brain Rhythms inhibitory neurons cortex …

… Statistical model defines ketamine anesthesia’s effects on the brain September 3, 2021 … the brain state changes that patients experience under ketamine-induced anesthesia. consciousness anesthesia EEG … the brain state changes that patients experience under ketamine-induced anesthesia By developing the first …

… drugs might be effective antidepressants (so far only ketamine is used that way). One theory holds that depression … depression, Brown’s review describes how drugs including ketamine, propofol, and dexmedetomidine directly intersect with the mechanisms underlying these theories. Ketamine increases BDNF and alters network connectivity. …

… unconsciousness under anesthesia consciousness anesthesia ketamine … under anesthesia At the level of molecules and cells, ketamine and dexmedetomidine work very differently, but in … from the paper summarizes the main findings. Under either ketamine or dexmedetomidine general anesthesia, brain waves …

… Brown has long studied how anesthetic drugs like propofol, ketamine, or dexmedetomidine produce states of … data from animals and EEG data from humans to establish ketamine’s brain wave signature . Unlike with propofol, ketamine-mediated unconsciousness included periods of …

… brain activity in mice. Specifically, he was interested in ketamine, a fast-acting antidepressant prone to being abused, with the hope that better understanding how ketamine works will help scientists find safer alternatives. … storage. His findings, Murdock explains, suggested that ketamine works by recovering dendritic spines that can be …

… student Indie Garwood described how the lab has shown how ketamine general anesthesia works. They’ve found that it … in the operating room, improving understanding of how ketamine affects the brain at a systemic level, and understanding more about how drugs like ketamine affect consciousness. Brown lab graduate student …

… how the drugs work. anesthesia consciousness propofol ketamine At Neuroscience 2022, Emery N. Brown relayed how … around the brain, leading to unconsciousness. Ketamine, which targets both inhibitory and excitatory …

… the brainstem, the thalamus, and cortex. By contrast, ketamine targets glutamate receptors both on peripheral … antinociceptive actions of six classes of drugs: opioids, ketamine, dexmedetomidine, magnesium, lidocaine, and NSAIDs …