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… levels in the brain of the CPG2 protein, a product of the SYNE1 gene which had been established as a genetic hit for … patient mutations (or combinations of them) in the part of SYNE1 controlling CPG2 expression and showed that they led to … that testing people for particular mutations of SYNE1 could be a biomarker of bipolar disorder risk. Such an …

… disorder (BD) and shows how specific mutations in the SYNE1 gene that encodes the protein undermine its expression … are not suggesting that the CPG2-related variations in SYNE1 are “the cause” of bipolar disorder, but rather that … in brain circuits. When genetic studies identified SYNE1 as a risk gene specific to bipolar disorder, Nedivi’s …

… bipolar disorder and showed how specific mutations in the SYNE1 gene that encodes CPG2 undermine the protein’s …

… had reduced levels of CPG2 because of variations in the SYNE1 gene . When they cloned these variants into rats, they …