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… in studying Down syndrome’s impact in the brain at the cellular and genomic level, examining key differences in gene … induced pluripotent stem cells. At the molecular and cellular level, Professor Manolis Kellis, director of MIT’s … samples to understand the genes, molecular pathways, and cellular states that play causal roles in cognitive …

… nervous system and to uncover mechanisms of how specific cellular functions become compromised in neurodegenerative … body,” Prescott said. “It’s really revolutionized a lot of cellular biology and molecular neuroscience.” In a preprint … profiling facilitates a nuanced portrait of the diverse cellular processes perturbed in the AD brain,” they wrote. …

… evidence that GENUS helps to stimulate the brain at the cellular and molecular level to mount a homeostatic response …

… the conceptualization of overlapping engram cells as the cellular foundation for representing generalizable knowledge … neuropsychiatric disorders, with a specific focus on the cellular and molecular mechanisms leading to experience … trying to develop advanced algorithms to take the spatial cellular architecture into account in brain image …

… therapeutics. We study disease pathogenesis both on the cellular and on the systems level, using a multidisciplinary … analyses In addition to investigating the molecular and cellular processes underlying Alzheimer’s disease and other … model systems for unraveling some of the molecular and cellular mechanisms underlying Alzheimer’s disease and for …

… are essential for autonomic health, yet their underlying cellular and molecular components remain poorly defined. We … and addressed at this vital barrier tissue. Molecular and cellular mechanisms of interoception How do physical cues get … tissues Neurons are long-lived effectors that coordinate cellular responses across vast distances. For example, …

… the viability of the cells, it is also changing other cellular processes such as division, differentiation and … more than controls. When the team looked at another cellular activity that could affect growth they found a …

… Aging Brain Initiative Symposium Cellular & Molecular Mechanisms of Neurodegeneration … for the MIT Aging Brain Initiative's bi-annual symposium,  Cellular & Molecular Mechanisms of Neurodegeneration , on … Intelligence Labs. The theme of this symposium is “Cellular & Molecular Mechanisms of Neurodegeneration.” --> …

… Astrocytes with the APOE4 variant show deficits of key cellular function, but overexpressing PICALM overcame the … provides a way of identifying how AD risk genes impact cellular biology, and how other genes can modulate these …