Site Search

… or “mini-brains.” To grow these cultures, a donor’s skin cells are reprogrammed to become induced pluripotent stem cells and those are then biochemically coaxed from that …

… to pinpoint what may be going wrong in specific brain cells and to help identify new treatment approaches. The … nervous system tissue, to precision genetic engineering of stem cells and animal models. This unique blend of … in a high throughput manner. Using induced pluripotent stem cells derived from patients, they will culture many …

… their future in research.  In the program undergraduate STEM majors from outside MIT spend the summer doing full-time … that, Baum not only is leading an organization advancing STEM education in Puerto Rico, but also is helping to mentor …

… iPS Core Facility The advent of human induced pluripotent stem cells (iPSCs) has heralded a new generation of clinical and … in human cells. The advent of human induced pluripotent stem cells (iPSCs) has heralded a new generation of clinical …

… through brain tissue delivering nutrients and oxygen that cells need and carrying away waste. Since Nedergaard’s … grafts in animal models. Zooming out to the level of brain cells, circuits and behavior, Institute Professor Ann … of the neuromodulator dopamine and non-neuronal companion cells called astrocytes. Improving care for people with brain …

… brain development. To make organoids, scientists take skin cells from a donor, induce them to become stem cells and then culture those in a bioreactor, guiding … factors and other chemicals. Over the course of weeks, the stem cells become progenitor cells that multiply and then go …

… expression of another Alzheimer’s-associated gene in those cells could help alleviate the problem. About 25 percent of … such as these cells derived from induced pluripotent stem cells, are critical for brain function. The research … a series of lab experiments in cultures of stem cell-derived human astrocytes and genetically engineered …

… cutting-edge model of the human blood-brain barrier using stem cells to investigate the effects of an Alzheimer’s risk gene. … an assistant professor at Mt. Sinai, he continues to use stem cells to study aging and neurodegenerative disease. In …