Research Topics

As this gallery of featured people and projects illustrates, Picower Institute scientists study brain structure and function at scales from genes and molecules to cells, circuits and regions. They also study the behaviors and cognitive processes that result, and seek to uncover how disruptions at different scales can result in developmental, psychiatric or neurodegenerative disorders. They employ—and often invent—the newest technologies in their work. To learn more about any of these specific areas, click "Research Topics" above, select areas of interest, and you'll find relevant Picower people, discoveries and events.

Cellular reprograming implicated in model of Alzheimer's disease

October 17, 2017
Research Findings
Neuroscientists identify genetic changes in microglia in a mouse model of neurodegeneration and Alzheimer's disease.

Brain waves reflect different types of learning

October 11, 2017
Research Findings
For the first time, researchers have identified neural signatures of explicit and implicit learning.

Kay Tye receives NIH Pioneer Award

October 5, 2017
Awards
The award will be used to map the neural circuitry of social interactions and develop a mathematical model for complex group behaviors.

How we recall the past

August 17, 2017
Research Findings
Neuroscientists discover a brain circuit dedicated to retrieving memories.

Blocking a key enzyme may reverse memory loss

August 8, 2017
Research Findings
MIT study suggests a new approach to developing treatments for Alzheimer’s disease.

New tool offers snapshots of neuron activity

June 26, 2017
Neurotechnology
FLARE technique can reveal which cells respond during different tasks.

A noninvasive method for deep brain stimulation

June 1, 2017
Research Findings
Electrodes placed on the scalp could help patients with brain diseases.

Brain circuit enables split-second decisions when cues conflict

April 24, 2017
Research Findings
New findings shed light on how we quickly assess risks and rewards before acting.

Neuroscientists identify brain circuit necessary for memory formation

April 6, 2017
Research Findings
New findings challenge standard model of memory consolidation.

Scientists identify brain circuit that drives pleasure-inducing behavior

March 22, 2017
Research Findings
Surprisingly, the neurons are located in a brain region thought to be linked with fear.

Unique visual stimulation may be new treatment for Alzheimer’s

December 7, 2016
Research Findings
Noninvasive technique reduces beta amyloid plaques in mouse models of Alzheimer’s disease.

Creating therapies for Alzheimer's disease by targeting neural circuits

November 9, 2016
Research Findings
Study finds a complex series of molecular, cellular, circuit and network-level changes contribute to the progression of Alzheimer's.