A microscope view of several worms wriggling through a red-hued gel
April 20, 2026
How neurons sense bacteria in the gut
Three views of an organoid cell culture show the constiuent cells of the vaguely round, tangled mass of cells.  In the different views the cells are highlighted in different colors such as magenta and green.
April 14, 2026
Rett syndrome study highlights potential for personalized treatments
A video screenshot shows a grayscale worm twisting its body around in a loop to change direction
April 10, 2026
With navigating nematodes, scientists map out how brains implement behaviors
A member of a surgical staff holds a mask on the face of an unconscious patient in an operating room
March 17, 2026
Three anesthesia drugs all have the same effect in the brain, MIT researchers find
Li-Huei Tsai stands at a podium embossed with an MIT logo. In the foreground is an attentive audience. In the background is the Picower Institute logo
March 11, 2026
After 16+ years leading Picower Institute, Li-Huei Tsai will sharpen focus on research, teaching

‘Skyrocketing’ research by investing in young researchers

June 23, 2020
Picower People
Picower Institute postdocs advance new ideas, gain skills with support of NIH’s ‘K99’ awards

Dopamine signaling allows neural circuits to generate coordinated behaviors

June 11, 2020
Research Findings
As part of study, team invents new open-source microscopy platform

Study finds path for addressing Alzheimer’s blood-brain barrier impairment

June 8, 2020
Research Findings
MIT researchers pinpoint mechanism and demonstrate drugs could help

Like a treasure map, brain region emphasizes reward location

June 1, 2020
Research Findings
Lateral septum encodes spatial information with a special emphasis on where the reward lies

Closing social distance with social media by highlighting a volunteer science movement

May 29, 2020
News Feature
While home from the bench, Tonegawa lab postdoc co-runs Twitter feed of the Covid-19 National Scientist Volunteer Database

McKnight Scholars Award supports Flavell lab’s gut-brain connection studies

May 28, 2020
Picower People
Award will help researchers understand how the body’s microbiome influences the brain

Research highlights immune molecule’s complex role in Huntington’s disease

May 26, 2020
Research Findings
Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice, affects neural connection genes

Grant fuels effort to develop new Alzheimer’s drug

May 22, 2020
New Research
Collaboration will develop compound to correct gene expression in brain’s immune cells

Scientists find a new way to reverse symptoms of Fragile X

May 20, 2020
Research Findings
Drug compound, tested in mice, could be effective in treating the leading heritable cause of intellectual disability and autism

Study finds that aging neurons accumulate DNA damage

May 18, 2020
Research Findings
Reactivating an enzyme that promotes DNA repair can help to reverse age-related cognitive decline in mice.

Technology makes tissues elastic and lasting for easier imaging

May 18, 2020
Research Findings
By making brain and other tissues reversibly stretchable or compressible, ELAST allows labeling probes to infuse more quickly

Study finds ‘volume dial’ for turning neural communication up or down

May 6, 2020
Research Findings
The protein Synaptotagmin 7 limits supply of neurotransmitter-containing vesicles for release at synapses