Extra chromosome alters chromosomal conformation and DNA accessibility across the whole genome in neural progenitor cells, disrupting gene transcription and cell functions much like in cellular aging.

How bold new neuroscience research projects get off the ground

Moms infected during pregnancy who produce elevated levels of the cytokine IL-17a may have microbiome alterations that prime offspring for aberrant immune responses later in life, mouse study suggests

Tomosyn’s tight regulation of neurotransmitter release distinguishes functions of two neuron classes at the fly neuromuscular junction

By integrating multiple sensory inputs, a loop of mutual inhibition among a small set of neurons allows worms to switch between long-lasting behavioral states

Picower scientists shared research on brain waves, new technologies, brain plasticity and psychiatric illness and, of course, learning and memory.

The findings may help explain why some people who lead enriching lives are less prone to Alzheimer’s and age-related dementia

Scholars from around the world gathered online to share new research on how intricately structured neural processes enable plasticity of circuit connections and help integrate incoming information to enable brain function

Large-scale, integrated application of advanced computational, biological techniques aims to discover mechanisms underlying ALS and frontotemporal lobar degeneration with motor neuron disease

While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental critical period

How brain circuits integrate many sources of context to flexibly guide behavior

As a researcher studying Huntington’s disease, and as a science communicator working tirelessly to keep Portuguese- and Spanish-speaking communities informed about Covid-19, Izabella Pena is focused on keeping people safe.