A microscope view of several worms wriggling through a red-hued gel
April 20, 2026
How neurons sense bacteria in the gut
Three views of an organoid cell culture show the constiuent cells of the vaguely round, tangled mass of cells.  In the different views the cells are highlighted in different colors such as magenta and green.
April 14, 2026
Rett syndrome study highlights potential for personalized treatments
A video screenshot shows a grayscale worm twisting its body around in a loop to change direction
April 10, 2026
With navigating nematodes, scientists map out how brains implement behaviors
A member of a surgical staff holds a mask on the face of an unconscious patient in an operating room
March 17, 2026
Three anesthesia drugs all have the same effect in the brain, MIT researchers find
Li-Huei Tsai stands at a podium embossed with an MIT logo. In the foreground is an attentive audience. In the background is the Picower Institute logo
March 11, 2026
After 16+ years leading Picower Institute, Li-Huei Tsai will sharpen focus on research, teaching

Summer students thrive in Picower labs

August 11, 2021
Picower People
Undergraduates from colleges across the country gain scientific training, mentorship and experience as participants in the MIT Summer Research Program

Brain’s ‘memory center’ needed to recognize image sequences but not single sights

July 26, 2021
Research Findings
The visual cortex stores and remembers individual images, but when they are grouped into a sequence, mice can’t recognize that without guidance from the hippocampus

Grant to help scientists test whether brain region is a key locus of learning

July 23, 2021
New Research
Long thought of as a generic alarm system, the locus coeruleus may actually be a sophisticated regulator of learning and behavior, an MIT team posits

Memory making involves extensive DNA breaking

July 6, 2021
Research Findings
To quickly express genes needed for learning and memory, brain cells snap both strands of DNA in many more places and cell types than previously realized, a new study shows

Bear earns amblyopia research award

June 28, 2021
Picower People
RPB Walt and Lilly Disney Award will support efforts to develop new therapeutic approach

As novel sights become familiar, different brain rhythms, neurons take over

June 8, 2021
Research Findings
As ‘visual recognition memory’ emerges in visual cortex, one circuit of inhibitory neurons supplants another and slower neural oscillations prevail

Postdocs earn interdisciplinary Schmidt Science Fellowships

June 3, 2021
Picower People
Selective global honor supports researchers in new scientific pursuits

Speakers describe systemic sources of, prescribe empathic responses to, early life stress

May 17, 2021
Recent Events
At symposium, science and stories converge on harms of early exposure to trauma, racism but also restorative power of understanding, nurturing, and extending opportunity

Picower Institute faculty commit to reducing post-pandemic air travel

May 12, 2021
Picower People
Climate action aims to drive down estimated greenhouse gas emissions to no more than half of pre-pandemic levels

In ‘minibrains,’ hindering key enzyme by different amounts has opposite growth effects

May 10, 2021
Research Findings
Surprising findings can help improve organoid cultures, explain role of GSK3-beta in brain development

New algorithms show accuracy, reliability in gauging unconsciousness under general anesthesia

May 6, 2021
Research Findings
Machine learning software advances could help anesthesiologists optimize drug dose

Anesthesia doesn't simply turn off the brain, it changes its rhythms

April 27, 2021
Research Findings
Simultaneous measurement of neural rhythms and spikes across five brain areas in animals reveals how propofol induces unconsciousness