Select Topics
Disorders
Cognition and Motivation
Systems Neuroscience
Molecular and Cellular
Neurotechnology

'Cellf' Expression

December 20, 2023
Research Feature
Picower Institute scientists are using single cell genomics techniques to measure gene expression and produce unque insights into nervous system biology and disease

Evidence early, but emerging, that gamma rhythm stimulation can treat neurological disorders

December 20, 2023
Research Feature
A new review surveys a broadening landscape of studies showing what’s known, and what remains to be found, about the therapeutic potential of non-invasive sensory, electrical or magnetic stimulation of gamma brain rhythms.

Nanoparticle-delivered RNA reduces neuroinflammation in lab tests

December 11, 2023
Research Findings
In mice and human cell cultures, MIT researchers showed that novel nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s disease

Emery N. Brown elected member of American Philosophical Society

November 28, 2023
Picower People
Brown elected to 2023 class of new members of the oldest learned society in the United States, co-founded by Benjamin Franklin.

How a mutation in microglia elevates Alzheimer’s risk

November 16, 2023
Research Findings
A new MIT study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways

Anesthesia blocks sensation by cutting off communication within the cortex

November 8, 2023
Research Findings
Under propofol general anesthesia, sensory input still reaches the brain, but signals do not spread. Results suggest consciousness requires cortical regions to all be “on the same page.”

Award honors Elly Nedivi’s research on cortical plasticity

November 6, 2023
Picower People
The Krieg Cortical Kudos Discoverer Award recognizes Nedivi’s ongoing work to understand molecular and cellular mechanisms that enable the brain to adapt to experience

New grant to study possibility of an immunotherapy for autism

November 2, 2023
New Research
Picower Institute-based collaboration will study mechanisms that might enable peripheral immune cells to deliver a potentially therapeutic molecule to the brain.

Aging Brain Initiative symposium showcases ‘cutting edge’ research across MIT

November 1, 2023
Picower Events
Seed projects, posters represent a wide range of labs working on technologies, therapeutic strategies, and fundamental research to advance understanding of age-related neurodegenerative disease

Anesthesia technology precisely controls unconsciousness in animal tests

October 31, 2023
Research Findings
An advanced closed-loop anesthesia delivery system that monitors brain state to tailor propofol dose and achieve exactly the desired level of unconsciousness could reduce post-op side effects

Mark Bear wins SfN’s Julius Axelrod Prize

October 30, 2023
Picower People
Society for Neuroscience Award recognizes Professor Mark Bear’s synaptic plasticity research, its translation to potential amblyopia and autism treatments, and his career of mentorship.

A multifunctional tool for cognitive neuroscience

October 20, 2023
Research Findings
A flexible new tool both monitors and manipulates neural activity in the brains of large animals.