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Disorders
Cognition and Motivation
Systems Neuroscience
Molecular and Cellular
Neurotechnology

Memory Systems

Memories can be of many types (e.g. places or faces), operate on different timeframes (long- or short-term), and be stored and recalled through distinct processes involving multiple brain regions. The subject of intense interest across the Picower Institute, memory systems are studied widely and in depth.  

Visual System

Perhaps the most prized of our senses, the visual system has long provided neuroscientists a model for studying neural plasticity and development and cortical dynamics. It also is a system in which disorders can produce devastating disabilities. At the Picower Institute, scientists study this system to gain broad insights into the brain and also to address societal needs.

Neuro Genomics and Proteomics

Fundamentally the central nervous system is made up of cells whose functions are specified by which genes are expressed, and how and when.  At the Picower Institute, scientists use “big data” and bio-informatics techniques to make new discoveries about how genes and the proteins that arise from their expression influence brain function and how abnormalities contribute to disease.

Brain Imaging

In many ways, Picower Institute neuroscientists are explorers for whom new ways to see inside the brain are essential for finding answers to their questions about how the brain works at scales ranging from synapses to whole networks. Researchers at the institute doesn’t just apply the latest imaging techniques, it often creates new technologies to make imaging better.

Cognition and consciousness arise from analog computations, says new theory

August 19, 2026
Research Findings
The brain's ability to generate quick, nimble volitional thought—and a unified awareness of thought and experience—arises from analog computations carried out by electrical waves, MIT neuroscientists argue in a new review

Flexible brain circuits can switch between different tasks

August 17, 2026
Research Findings
Neuroscientists have discovered circuits in the prefrontal cortex that can be repurposed to store different types of information.

High-speed microscopy reveals electrical activity across the brain

August 14, 2026
Research Findings
The new technique could help scientists learn how the entire brain works to generate decisions and emotions.

Brain circuit keeps tabs on what just happened to aid judgement of what’s happening now

August 13, 2026
Research Findings
With the tough job of trying to keep track of what’s going on in front of it, the brain relies not only on what it sees, but also a comparison with what it just saw. A new study in mice pinpoints the circuit that provides that service.

With Mass. Women’s Health Award, team will study how Alzheimer’s risk varies with hormone replacement

July 29, 2026
New Research
Observations conflict about whether hormone replacement therapy increases or decreases Alzheimer’s likelihood for women. With a new award from the Massachusetts Life Sciences Center, MIT researchers will investigate the underlying molecular mechanisms aff

A new director

July 27, 2026
Picower People
Myriam Heiman becomes the fourth director of The Picower Institute. She shares her outlook in a new Q&A

MIT names Emery N. Brown an "Institute Professor," its highest faculty honor

July 20, 2026
Picower People
Brown, a renowned neuroscientist, anesthesiologist and statistician, has made numerous seminal contributions to basic science and clinical care alike. He joins two other professors in earning the honor this year

Picower Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86

July 15, 2026
Picower People
Tonegawa made landmark discoveries about how the immune system generates antibody diversity and how the brain forms memories.