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… is a leading researcher in spatial biology, pioneering the development of next-generation spatial metabolomics to decode …

… Article Study finds circular RNA helps drive brain development October 16, 2025 Research Findngs Study finds circular RNA helps drive brain development MIT neuroscientists show in a new study that … neurons build circuit connections, or synapses, during the development of the visual system in young mice. Read more …

… factors, such as maternal infection during fetal development, also play a role. Given the complexities, … strategy, the study demonstrated ways to rescue synapse development. Now Littleton’s lab has embarked on another … studies revealing how MeCP2 mutations disrupt brain development. A 2017 study found that mutations can lead to …

… autism. To set the stage for potential drug development, Littleton’s lab was able to demonstrate ways to bypas s Wnt signaling that rescued synaptic development.   Shank3 mutation: In the top image, a neuronal … activity of the visual system to that observed in early development and enables growth of responses to the amblyopic …

… says Gloria Choi, the Samuel A. Goldblith Career Development Assistant Professor of Brain and Cognitive …