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… follows a progression through many regions of the cortex, and not exactly in the way many neuroscientists would … the Proceedings of the National Academy of Science . “The cortex is not modular,” said Earl Miller , Picower Professor … and Cognitive Sciences at MIT. “Different parts of the cortex emphasize different things and do different types of …

… Processing Public Event Abstract:   The primate prefrontal cortex shares a dense network of reciprocal anatomical … and its relevance to computations performed by prefrontal cortex.  Work in our lab has been using electrode arrays in prefrontal cortex and interconnected cortical areas to record the …

… chemical acetylcholine in the brain’s outer surface, or cortex, the brain exhibits relatively high-frequency, … have shown that the hippocampus communicates with the cortex during sleep as it replays representations of … the peaks or “up states” of slow waves, the prefrontal cortex (the locus of reasoning and executive function) …

… When researchers knocked down a Mef2 gene in the frontal cortex of mice (blank areas), it prevented the mice from … in a subpopulation of excitatory neurons in the prefrontal cortex of resilient individuals. To study cognitive … researchers knocked out the gene for MEF2 in the frontal cortex, this blocked the mice’s ability to benefit from being …

… focused on the hippocampus, overlying regions like the cortex remained unaffected. This overcomes a drawback of … to affect behavior: By moving the signal around the motor cortex, they compelled mice to move different body parts. … showed that entraining the gamma rhythm in the visual cortex coordinated beneficial activity, for instance …

… by coordinating ensembles of cells, or neurons, in the cortex with timely bursts of activity at the frequencies of … beta waves originate from deeper layers of the prefrontal cortex, while gamma waves originate in more superficial … as neuroscientists had previously observed in the visual cortex. “This model brings together the maintenance and …

… by imaging layers of neurons in the somatosensory cortex of mice, after expanding the tissue volume fourfold. … compare the density of synapses in different parts of the cortex. Using this technique, it is possible to analyze … “We counted clusters of postsynaptic markers across the cortex, and we saw differences in synaptic density in …

… develop new therapeutic approach amblyopia vision visual cortex visual system LTD RPB Walt and Lilly Disney Award will … In decades of investigating the development of visual cortex, Bear’s lab has discovered fundamental mechanisms of … of normal vision, the connections from that eye to visual cortex undergo a process called “long-term depression” (LTD). …