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… from the nucleus to the rest of cells – a generally vital function. It is particularly important in the immune system … in people with 16p11.2 deletion syndrome, its specific function in neurons has barely been investigated. To change … less electrical current across their excitatory synapse connections with other neurons, suggesting reduced …

… might not only include understanding healthy higher-level function but also how those functions become disrupted in …

… Level Cognition Computational Neuroscience Executive Function Glia Neuromodulators cerebral cortex plasticity … The brain is shaped by learning and memory, and its function is importantly modulated by internal states such as … approaches for recording the activity and analyzing the function of neurons, astrocytes, synapses and circuits of the …

… Genomics and Proteomics Brain Imaging Neural Circuits Synapse Mapping Public Event The Picower Lecture with Hongkui … Brain Cell Type Diversity Abstract: To understand the function of the brain and how its dysfunction leads to brain … with each other and what their roles are in circuit function. At the Allen Institute, we have built multiple …

… diseases. Sheng’s molecular studies of the structure and function of synapses (the communication junctions between … our understanding of the neural basis of cognitive function and dysfunction, including learning and memory, … discoveries regarding the molecular mechanisms of synapse weakening and loss, the contributions of microglia …