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Picower Research and Artificial Intelligence

… by Robots and Animals An integrative theory of prefrontal cortex function   An Emergent Model of Orientation … mechanisms of visual working memory in the prefrontal cortex of the macaque Statistical issues in the analysis of … Trajectory Encoding in the Hippocampus and Entorhinal Cortex Experience-dependent asymmetric shape of hippocampal …

With new grant, MIT neuroscientists will give 'invisible' cells a new look

February 08, 2018
… with neurons to process information astrocytes glia visual cortex synapse development Neurons are the star of the show … insight to discover that astrocyte activity in the visual cortex, the part of the brain that processes vision, matched … will monitor astrocyte and neuron activity in the visual cortex as mice see different stimuli. They’ll also use …

Behind the scenes, brain circuit ensures vision remains reliable

September 08, 2021
… governed by a circuit of inhibitory neurons vision visual cortex multiphoton microscopy visual system inhibitory … time, but instead different groups of cells in the visual cortex can become stimulated by the same scenes. So how does … images appear, thereby representing them in the visual cortex, activity among two types of “inhibitory” neurons …

How the brain is flexible enough for a complex world (without being thrown into chaos)

May 13, 2024
… among neurons particularly in the medial prefrontal cortex is key to enabling many mental abilities. "The mPFC is … about 30 percent of the neurons in the prefrontal cortex of the brain seemed to be involved. Skeptics who … of copious evidence—it has been observed across the cortex and in other brain areas such as the hippocampus and …

‘Rewiring’ cortical circuits

… such “monocular deprivation” can cause the visual cortex to rewire connections serving the occluded eye to … In 2010 they found that synaptic changes in the visual cortex following dark-rearing and then light exposure … after being reared in the dark, neurons in the visual cortex dramatically increased production of a microRNA called …

Studies help explain link between autism, severe infection during pregnancy

September 13, 2017
… inhibitory neurons autism spectrum disorders cortex proprioception … other. In this image: An irregularity in the somatosensory cortex, called a “patch,” can be seen as a cluster of blue in … the researchers call “patches” in certain parts of the cortex. In one of the new papers, the researchers set out to …

Paper: To understand cognition—and its dysfunction—neuroscientists must learn its rhythms

April 17, 2024
… “beta” band originate in deeper layers of the brain’s cortex and appear to regulate the power of faster-frequency … where gamma rhythms can encode information in the cortex, for instance from the senses. Some of the lab’s … control of cognitive processes to physical patches of the cortex, essentially acting like stencils that pattern where …

Visual Recognition Memory

… of Picower Professor Mark Bear have shown that the visual cortex is not just sorting out shapes, colors and motion, but … was trying to assay visual responses in the visual cortex of mice (V1) when he observed something surprising. … mouse brain section shows green highlighting in the visual cortex In a paper in 2015, the lab showed how SRP reveals the …
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