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… and brain-wide connectivity mapping, to characterize the molecular, anatomical, physiological, and connectional … cell type taxonomy and atlas. Zeng received her Ph.D. in molecular and cell biology from Brandeis University, where she studied the molecular mechanisms of the circadian clock in fruit flies. …

… for autonomic health, yet their underlying cellular and molecular components remain poorly defined. We employ a … encoded and addressed at this vital barrier tissue. Molecular and cellular mechanisms of interoception How do … We seek to understand how the nervous system adapts at the molecular, anatomical and circuit level in response to …

… pinpointed the specific vascular cell type (pericytes) and molecular pathway (calcineurin/NFAT) through which the APOE4 … pericytes’ increased activation of the calcineurin/NFAT molecular pathway appears to encourage the elevated APOE … and expression of the same key genes, proteins and molecular pumps as natural BBBs. When immersed in culture …

… for Learning and Memory report finding a key sequence of molecular events in which the genetic mutation in a fruit fly … in cortex glia cells causes them to hyper-activate a molecular pathway that leads them to withdraw many of the … detailed sequence of events, implicating several specific molecular players and processes. That richly built knowledge …

… is using single-cell RNA sequencing techniques to create molecular profiles of these changes. Audrey Effenberger … Myriam Heiman Effenberger seeks to better understand the molecular and functional diversity of non-neuronal cell types … Cassi Estrem Steve Flavell Estrem seeks to unveil the molecular mechanisms of how the nervous system senses signals …

… that arise—called gliomas—can hijack those cellular and molecular mechanisms. To promote their own growth, gliomas … many other diseases as well), but also revealed specific molecular factors involved. Those findings, Monje said, …