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40 Hz vibrations reduce Alzheimer’s pathology, symptoms in mouse models

May 18, 2023
… motor performance, reduced phosphorylated tau, preserved neurons and synapses and reduced DNA damage, a new study … DNA damage, a new study shows Evidence that non-invasive sensory stimulation of 40 Hz gamma frequency brain rhythms … reduce neural DNA damage. “This work demonstrates a third sensory modality that we can use to increase gamma power in …

Feast or forage: Study finds circuit that helps a brain decide

November 22, 2021
… 22, 2021 Research Findings By integrating multiple sensory inputs, a loop of mutual inhibition among a small set of neurons allows worms to switch between long-lasting … By integrating multiple sensory inputs, a loop of mutual inhibition among a small set …

As brain extracts meaning from vision, study tracks progression of processing

July 10, 2018
… A new study that tracked how the brain turns simple sensory inputs, such as “green,” into meaningful categories, … of six cortical regions operated along a continuum between sensory processing and categorization. To be sure, general … were eavesdropping on the activity of hundreds of neurons in six regions across the cortex: prefrontal (PFC),  …

Circuit that focuses attention brings in wide array of inputs

April 21, 2022
… brain incorporates and integrates information to focus its sensory resources on its goals. Working in mice, the team … smaller and less evolved than the pulvinar. ACC-projecting neurons visible in the LP region of a mouse brain “In these … information as well. “We’re seeing that it’s not just sensory—there are so many inputs that are coming from …

Tsai presents non-invasive stimulation study at Massachusetts Down Syndrome Congress

March 27, 2024
… benefits. With early studies indicating that non-invasive sensory stimulation of a gamma frequency brain rhythm may … band frequency of the brain associated with processing sensory information and also memory and cognition. Finding a … health-promoting changes in brain cells including neurons, astrocytes and the brain’s vasculature. One of the …

40Hz rhythms fight Alzheimer’s at the cellular and molecular level

… light and sound together was especially powerful. Above: Sensory exposure to 40Hz light prevented neurodegeneration in … Alzheimer's mouse brain is on the left. One treated with sensory stimulation is on the right. Importantly the MIT team … reflected in substantial changes in gene expression in neurons and microglia that the team measured in mice exposed …

A noninvasive treatment for “chemo brain”

March 06, 2024
… to the chemotherapy drug cisplatin. Mice treated with 40Hz sensory stimulation (right) showed much less DNA damage than mice that did not receive 40Hz sensory stimulation (left). Tsai, who also leads MIT's Aging … loss of myelin, the protective fatty coating that allows neurons to propagate electrical signals. Many of these …
From: https://picower.mit.edu/search