… scientific interest they share: the dysfunction of cells called astrocytes in disease. Loon is interested in the cells in the context of Alzheimer’s disease so she said she … for The Picower Institute community. 28 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …
… mechanism that helps neurons form memories in the first place. In studying mice modeling Alzheimer’s, Tsai’s lab … realized, not only in neurons but also in other brain cells called glia. …
… and express an inserted version in precisely targeted cells. This allowed them to quickly and precisely alter a … Because of the use of a virus to alter DNA in post-mitotic cells, this technique allowed the interrogation of molecular … of structure and function within finely targeted cells or brain regions. The technique has become one in which …
… immune molecule called IL-17a, which is produced by immune cells during a fever, can temporarily reduce some of the … interesting.” --From MIT News 443 3 20 14 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …
… findings — which come in large part from tweaking nerve cells, and behaviors, in lab animals — have led to a deeper … After a series of experiments on how certain nerve cells respond to cocaine, the data were in shambles. But Tye … the mice didn’t seem to like the sensation, avoiding a place where the stimulation happened, the artificial kick …
… to culture cerebral organoids, or “minibrains,” using stem cells derived from people has given scientists experimentally … recognize and track architectural patterns formed by the cells as the organoids develop or are affected in models of …