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Behind the scenes, brain circuit ensures vision remains reliable

September 08, 2021
… consistency in representation is governed by a circuit of inhibitory neurons vision visual cortex multiphoton microscopy visual system inhibitory neurons inhibitory circuits … only inhibit excitatory cell activity via connections, or “synapses,” on the spiny tendrils called dendrites that extend …

Many Mechanisms of Mood

September 29, 2025
… among neurons. Yet another theory focuses on the inhibitory neurotransmitter GABA, suggesting that reduced … how neurons forge and edit their circuit connections, or “synapses,” to enable the brain to flexibly respond to … receptors for the neurotransmitter glutamate at excitatory synapses. This doesn’t immediately explain why a deficit …

Resolving a seeming contradiction, study advances understanding of visual recognition memory

September 27, 2023
… For 20 years Bear’s lab has been investigating how the synapses involved in VRM change by studying a phenomenon … brain region that relays sensory information) and to inhibitory neurons in layer 4, where they had first measured … in a higher “gamma” frequency that depends on one kind of inhibitory neuron, but as it becomes more familiar, the …

The unexpected precision of an inducible transcription factor

… This information is then converted into precise changes in inhibitory circuit connectivity that reconfigures the … of Npas4, we find NPAS4 selectively regulates synapses made by two different populations of CCK inhibitory neurons and coordinates excitation and inhibition …

‘Rewiring’ cortical circuits

… between two neurons called a synapse and that most of the synapses neurons form to receive input from others reside on … the fate of the spines on those dendrites that house many synapses. In 2003, for example, the lab showed an important … too. The Sur lab has not only looked at changes among synapses on dendritic spines, but also at the underlying …
From: https://picower.mit.edu/search