… of Rett syndrome, mutations in the gene MECP2 lead to synapse- and circuit-specific problems in the maturation and … role of IGF1 downstream of MeCP2 in regulating synaptic function. In a 2009 paper , Sur's lab led by Daniela Tropea …
… neurons that died during disease, restoring the essential function of producing the neurotransmitter dopamine. Above: … may cause further protein aggregation that affects brain function. One of the proteins whose aberrant behavior is most …
… a full memory when only given incomplete cues (a mental function called pattern completion). Five years later they … transmission in hippocampal circuits to determine their function. The innovative study showed that a long circuit …
