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… Findings A breakdown of lipid metabolism in these brain cells promotes inflammation and interferes with neuron activity, a new study finds organoids iPSCs stem cells neurodegeneration ApoE lipid metabolism https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00300-9 A breakdown of lipid …

… and brain research on field trips to MIT DEIJ Evolution stem cells synapse function visual cortex iPSCs Teens from area … describes processes used to turn induced pluripotent stem cells into brain cells. On March 29, for instance, …

… research labs at MIT to get information and inspiration stem cells autism drosophila neurodegeneration DEIJ Just before … careers. “It helps them focus on the different fields of STEM they could choose,” said Everett Academy Lead Teacher …

… mutation that alters a protein in the brain’s immune cells, known as microglia, can give people as much as a … on human microglia cell cultures. To do this they used a stem cell line derived from skin cells donated by a healthy 75-year-old woman. In some of the stem cells they then used CRISPR gene editing to insert the …

… the more common form of the gene, APOE3. Studying brain cells derived from a type of induced human stem cells, the researchers found that APOE4 promotes the … to answer that question using human induced pluripotent stem cells — stem cells derived from skin or other cell …

… Human Models of Disease December 16, 2019 News Feature Stem cell, genetic technologies enable sophisticated studies of human brain cells and brain "organoids" For decades, neuroscientists … and to “reprogram” it to become an “induced pluripotent stem cell” (iPSC) that can then be biochemically guided to …

… neurodevelopmental disorder Rett syndrome CRISPR/Cas9 stem cells neurodevelopmental disorders autism spectrum disorders … KCC2 gene activity. Using CRISPR/Cas9 genome editing and stem cell technologies, they engineered human neurons to …

… their future in research.  In the program undergraduate STEM majors from outside MIT spend the summer doing full-time … that, Baum not only is leading an organization advancing STEM education in Puerto Rico, but also is helping to mentor …

… to pinpoint what may be going wrong in specific brain cells and to help identify new treatment approaches. The … nervous system tissue, to precision genetic engineering of stem cells and animal models. This unique blend of … in a high throughput manner. Using induced pluripotent stem cells derived from patients, they will culture many …

… through brain tissue delivering nutrients and oxygen that cells need and carrying away waste. Since Nedergaard’s … grafts in animal models. Zooming out to the level of brain cells, circuits and behavior, Institute Professor Ann … of the neuromodulator dopamine and non-neuronal companion cells called astrocytes. Improving care for people with brain …