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… arousal in locus coreuleus Neuromodulators inhibitory neurons prefrontal cortex arousal optogenetics multiphoton … how does this come about?” Locus coeruleus noradrenergic neurons appear in red and GABAergic ones are in cyan. An NA … One type came about from those inputs – for instance from sensory processing circuits – that simultaneously connected …

… and many others, suggesting that that the LC may integrate sensory inputs and internal cognitive states from across the … the pitch is low the LC would send less NE via a cadre of neurons to the motor cortex, reflecting the animal’s belief … Not only will the team be measuring the activity of LC-NE neurons, they’ll also take them over using optogenetics (in …

… key proteins called NMDA receptors act specifically in neurons in layer 4 of the visual cortex to make the circuit … the evidence demonstrates that NMDA receptors in layer 4 neurons are indeed necessary for the degradation of vision in … circuits modified to enhance cortical responses to sensory inputs during deprivation or to stimuli that have …

… spanning distant regions down to individual synapses where neurons connect. The collaboration will take advantage of … in the visual cortex to watch how it responds to specific sensory inputs. What would take 10 hours with a conventional … which is enough to reach down to dendritic spines of neurons in layer 5 of the cortex, an important area of …

… normal rhythms that synchronize such brain functions as sensory perception, higher cognition or motor control. … Ken Solt showed how stimulating dopamine-producing neurons in the ventral tegmental area of the brain could wake …

… to spur larger-scale testing and development of 40Hz sensory stimulation. Earlier this year the company launched … becomes overactive in Alzheimer’s, restores the ability of neurons to forge connections that sustain learning and …

… of the potential therapy, called Gamma ENtrainment Using Sensory Stimuli (GENUS), in humans to test its safety and … can be turned into stem cells, which in turn can grow into neurons or heart cells. MIT biology Professor Laurie Boyer , … other experiments with patient-derived cells—in this case, neurons— Lindy Barrett of the Broad Institute of MIT and …

… by the environment. In plasticity, the connections between neurons, or synapses, get stronger or weaker. Nedivi wanted … regulates receptors at the synapses of glutamate-producing neurons. CPG2 also happens to be the product of  a gene that … and repurposing unused neural resources to go where the sensory action was. ‘Rewired’ ferrets could use their …

… he dedicated himself to studying how large groups of neurons in the hippocampus and other brain regions represent, … by the senses), depends on higher-frequency waves from sensory cortices. Miller continues to explore how other …