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… imaging techniques to reveal fundamental mechanisms of memory, how animals learn to intelligently navigate their … in the hippocampus changes circuit connections to encode spatial memories. Linlin Fan created this black and white … ultimately produces an enduring neural encoding of that memory, Fan is eager to push the limits of “all optical …

… of Neuroscience in The Picower Institute for Learning and Memory at MIT. “If you remove astrocytes from a culture in a … in living animals wherever in the brain they want (spatial control) and with the timing of their choosing … the CRISPR/Cas9 gene editing technique to knock out with spatial and temporal precision two genes that allow …

… Circuit Genetics at The Picower Institute for Learning and Memory and Howard Hughes Medical Institute. Pharmacological … control LC noradrenergic neurons in mice with temporal and spatial precision as the rodents engaged in three attentional … on a second behavioral paradigm, derived from the Posner spatial cueing task, widely used in human cognitive …

… so to understand how they produce brain functions such as memory, neuroscientists must track how their voltage … scholar in The Picower Institute for Learning and Memory lab of Sherman Fairchild Professor Matt Wilson , is a … (BCS), whose lab studies how the brain encodes and refines spatial memories both during wakeful exploration and during …

… the sleeping brain to reveal hidden memories. hippocampus memory consolidation … Matthew Wilson  at the  Picower Institute for Learning and Memory  study how activity of a brain region called the hippocampus — which is critical for spatial memories and memories of specific events — relates to …

… and a member of MIT’s Picower Institute for Learning and Memory. The new findings, reported today in Neuron , could … the brain that are involved in vision, sound processing, spatial awareness, and executive function.  These recordings …

… for repairing age-related DNA damage to genes involved in memory and other cognitive functions. This enzyme is often … , the director of MIT’s Picower Institute for Learning and Memory and the senior author of the study. “I think this is a … HCAC1 also showed impairments in tests of memory and spatial navigation. The researchers found that HDAC1 loss led …

… MIT scientists at The Picower Institute for Learning and Memory shows that propofol substantially alters how different … they cover. These include reading information out from memory and holding it there while it waits to be used in … waves become planar rather than rotating, disrupting this memory-aiding mechanism and depriving the brain of a key …

… in our thinking and wellness Sleep oscillations memory consolidation replay reverse replay arousal … It's just a different kind of activity.” Sleep improves memory and maintenance Wilson investigates how brain makes … “down” state in the retrosplenial cortex, (which considers spatial contexts). The lab is currently working on decoding …

… are protected from degeneration and learning and memory endure significantly better than in disease model mice … and director of The Picower Institute for Learning and Memory. Adaikkan has been interested in understanding how … explained. The Tsai lab’s has shown significant effects on spatial memory and some effects on other forms of memory, …