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… Award recognizes Nedivi’s ongoing work to understand molecular and cellular mechanisms that enable the brain to adapt to …

… how non-neural cells indispensably contribute to function, and why their roles can make them promising treatment targets … Vascular cells: In 2022, Heiman co-led one of the first cellular “atlases” of the brain’s vasculature . Her team … and responsive tissues that stringently filter what molecular materials can move through the “blood-brain …

… 428 donors, revealing insights for Alzheimer’s onset and potential treatments. neurodegeneration dementia blood … of MIT and Harvard recently unveiled a systematic molecular atlas of human brain vasculature and its changes in … and multiple sclerosis. However, the molecular and cellular underpinnings of BBB dysregulation remain …

… see how disease affects major brain cell types and identify common, potentially targetable pathways … the disease’s disruptions converge on five main areas of cellular function, or “pathways,” in each of five major brain … in each. “By identifying vulnerable cell types and the molecular programs that give rise to them, therapeutic …

… a broadening landscape of studies showing what’s known, and what remains to be found, about the therapeutic potential … that they are also associated with specific changes at the cellular and molecular level. The 2016 study and many others since then …