Disorders

Picower Institute scientists investigate the pathophysiological mechanisms underlying complex disorders of the brain that affect emotion and cognition. To learn more about research in these or other areas, select them under "Research Topics" and you'll find relevant Picower people, discoveries and events.

April 20, 2022

New Research

Competitive seed grants launch yearlong investigations of novel hypotheses about potential causes, biomarkers, treatments of Alzheimer’s and ALS.

January 6, 2022

Research Findings

Extra chromosome alters chromosomal conformation and DNA accessibility across the whole genome in neural progenitor cells, disrupting gene transcription and cell functions much like in cellular aging.

December 20, 2021

Research Feature

How bold new neuroscience research projects get off the ground

December 7, 2021

Research Findings

Moms infected during pregnancy who produce elevated levels of the cytokine IL-17a may have microbiome alterations that prime offspring for aberrant immune responses later in life, mouse study suggests

November 3, 2021

Research Findings

The findings may help explain why some people who lead enriching lives are less prone to Alzheimer’s and age-related dementia

September 29, 2021

Research Findings

While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental critical period

July 23, 2021

New Research

Long thought of as a generic alarm system, the locus coeruleus may actually be a sophisticated regulator of learning and behavior, an MIT team posits

July 6, 2021

Research Findings

To quickly express genes needed for learning and memory, brain cells snap both strands of DNA in many more places and cell types than previously realized, a new study shows

June 3, 2021

Picower People

Selective global honor supports researchers in new scientific pursuits

May 17, 2021

Recent Events

At symposium, science and stories converge on harms of early exposure to trauma, racism but also restorative power of understanding, nurturing, and extending opportunity