The Chung Lab is an interdisciplinary research team devoted to developing and applying novel technologies for holistic understanding of large-scale complex biological systems. Specifically, we develop a host of methods including CLARITY (Nature, 2013), SWITCH (Cell, 2015), stochastic electrotransport (PNAS, 2015), MAP (Nature Biotechnology, 2016) and SHIELD (Nature Biotechnology, 2018) that may enable identification of multi-scale functional networks and interrogation of their system-wide, multifactorial interactions. We are applying these technologies for studying brain function and dysfunction using animal models, human clinical samples, and organoid systems.