Earl Miller

Earl Miller
Picower Professor of Neuroscience
The Picower Institute for Learning and Memory
Department of Brain and Cognitive Sciences
Massachusetts Institute of Technology

Office: 46-6241
Phone: 617-252-1584
Email: ekmiller@mit.edu
Website: http://earlkmiller.org

Administrative Assistant
Brenna Gray
Office: 46-6241
Phone: 617-252-1790
Email: bgray@mit.edu

Research

Neural Basis of Memory and Cognition
Interests in the Miller laboratory center around the neural mechanisms of attention, learning, and memory needed for voluntary, goal-directed behavior. Much effort is directed at the prefrontal cortex, a cortical region at the anterior end of the brain that is greatly enlarged in primates, especially humans. The prefrontal cortex has long been known to play a central role in cognition. Its damage or dysfunction disrupts the ability to ignore distractions, hold important information “in mind”, plan behavior, and control impulses. The lab explores prefrontal function by employing a variety of techniques including multiple-electrode neurophysiology, psychophysics, pharmacological manipulations, and computational techniques.

Recent work in the lab has shown that neurons in the prefrontal cortex have complex properties that are ideal for a role in cognitive control. Their activity is highly dependent on, and shaped by, task demands. They are selectively activated by relevant sensory inputs, involved in recalling stored memories, and they integrate the diverse information needed for a common behavioral goal. Perhaps most importantly, they transmit acquired knowledge. Their activity reflects learned associations between diverse stimuli, actions, and their consequences. They can even convey abstract behavioral information such as “rules.” This representation of the formal demands of tasks within the prefrontal cortex may provide the necessary foundation for the complex forms of behavior observed in primates, in whom this structure is most elaborate.

Short Bio

Earl K. Miller received his Ph.D. in Psychology and Neuroscience from Princeton University. After postdoctoral training at the National Institute of Mental Health, he joined the Department of Brain and Cognitive Sciences and the Picower Institute for Learning and Memory at MIT in 1995.

Awards
  • Distinguished Member, National Society of Collegiate Scholars, 2013
  • National Institute of Mental Health MERIT Award
  • Mathilde Solowey Award in the Neurosciences
  • Election to the International Neuropsychological Symposium
  • Fellow of the American Association for the Advancement of Science
  • The Picower Chair at MIT
  • The National Academy of Sciences Troland Research Award
  • The Society for Neuroscience Young Investigator Award
  • The Pew Scholar Award
  • The John Merck Scholar Award
  • The McKnight Scholar Award
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