July 20, 2026
Emery N. Brown, a physician and neuroscientist who studies how anesthesia affects the brain, is one of three MIT Professors to have been awarded MIT’s highest faculty honor: the title of Institute Professor. With the appointments of . Brown, Daniel Hastings SM ’78, PhD ’80, and Douglas Lauffenburger, there are now 12 Institute Professors at MIT, along with 10 Institute Professors Emeriti.
The appointments, which took effect July 1, were announced today in an email to the faculty from Sally Kornbluth, MIT’s president; Anantha Chandrakasan, MIT provost; and Roger Levy, chair of the faculty and a professor of brain and cognitive sciences.
Brown, who has been a member of the MIT faculty since 2005 and a member of the Picower Institute faculty since 2016, says he is “tremendously honored” to be appointed as an Institute Professor.
“It’s a pleasure to know that your colleagues hold you in such high esteem and that the work that you’re doing is valued,” says Brown, the Edward Hood Taplin Professor of Medical Engineering. “When you look down the list of people who have had this title, it’s an amazing group.”
After graduating from Harvard University with a bachelor’s degree in applied mathematics in 1978, Brown earned a PhD in statistics, also from Harvard, and an MD from Harvard Medical School. Since 1992, he has been a member of the Harvard Medical School faculty, and until recently he was a practicing anesthesiologist at Massachusetts General Hospital.
Throughout his career, Brown has made contributions in several different areas of neuroscience. In the early stages of his research career, he developed statistical methods to characterize the properties of the human circadian clock. He showed how light exposure can shift the phase of the human clock, depending on the circadian phase during which the light is administered. He also developed methods to demonstrate, from analyses of physiological data collected under special low-light conditions, that the intrinsic period of the human clock, like that of other species, is closer to 24 hours and not 25. Brown also measured the impact of shift work schedules that were designed using circadian physiology.
Later, he developed new statistical techniques and signal processing methods to analyze data collected in systems neuroscience experiments. As part of this work, he devised algorithms to decode the position of an animal in its environment by reading the activity of a small group of place cell neurons in the animal’s brain.
Joining MIT’s faculty just over 20 years ago represented an “inflection point” in his career, Brown says.
“I was an anesthesiologist doing statistical research, interested in neuroscience, and MIT allowed me to tie all those together,” he says. “I could work with colleagues who could help me understand the neuroscience of anesthesia, have another outlet for the statistical research that I was doing, and also more direct interactions with undergraduates and grad students.”
Over the past two decades, Brown has applied statistical techniques to studying what happens to the brain under anesthesia. His work has revealed how drugs such as propofol alter the brain’s intrinsic oscillations, which can be seen with electroencephalography (EEG).
During the awake state, these oscillations usually have high frequencies and low amplitudes, but as anesthetic drugs are given, they shift to low frequencies and high amplitudes. These changes disrupt normal communication between different brain regions, leading to loss of consciousness.
Brown has also shown that these EEG oscillations can be used to monitor whether a patient is too deeply unconscious, and he has developed a closed-loop anesthesia delivery system that can monitor these oscillations in real-time and guide anesthetic dosing during surgery.
In 2024, Brown was presented with the National Medal of Science. Among his other awards, he is also a recipient of a National Institute of Health Director’s Pioneer Award, the Gruber Prize in Neuroscience, and the Swartz Prize for Computational and Theoretical Neuroscience. He one of a small group of researchers to be an elected member of all three National Academies of Medicine, Sciences, and Engineering, as well as the National Academy of Inventors.
From 2012 to 2022, he served as co-director of the Harvard-MIT Program in Health Sciences and Technology. He has also played an instrumental role in several important efforts at MIT, including the 2010 Report on the Initiative for Faculty Race and Diversity, and the founding of the MIT Institute for Data, Systems, and Society (IDSS) in 2015.
Outside of his work at MIT, Brown served on President Obama’s Brain Initiative Working Group, as well as the National Academy of Sciences Committee on Women in Science and Engineering and the Council of the National Institutes of Neurological Disorders and Stroke.
Brown is also known for his commitment to teaching and mentoring students. In 2024, he was named a recipient of MIT’s “Committed to Caring” award — an honor given by MIT’s Office of Graduate Education to faculty members who have served as exceptional mentors to graduate students.
--For more see MIT News
