A security guard views a bank of eight monitors on his desk. The perspective of the image is from behind the security guard so that the various parts of a building's interior is visible on the monitors.
October 20, 2025
Like radar, a brain wave sweeps a cortical region to read out information held in working memory
Six panels show circular arrangements of each individual cell type in a miBrain culture, stained in cyan. The cell types are Pericytes, Astrocytes, Endothelial Cells, Neurons, Oligodendroglia, and Microglia
October 17, 2025
MIT invents human brain model with six major cell types to enable personalized disease research, drug discovery
An array of six panels shows different views of a long, thin, spiny structure that closely resembles a bumpy twig. Each is stained bright green and the degree of bumpiness varies along each one.
October 16, 2025
Study finds circular RNA helps drive brain development
Two stacked electron microscope images show a synapse. Above a small, river-like gap is a dark T shape among many tiny bubble-like circles. In the bottom image the T shape is much bigger than in the upper image.
October 14, 2025
Neural activity helps circuit connections mature into optimal signal transmitters
The almond shape of the amygdala is composed of cells stained red (on the left) and green (on the right).
September 29, 2025
Many Mechanisms of Mood

Spring break tours give high schoolers a chance to see science up close

March 31, 2023
Picower Events
Teens from area high schools got the chance to learn about advanced biology and brain research on field trips to MIT

‘Spatial Computing’ enables flexible working memory

March 15, 2023
Research Findings
Brain applies rhythms to physical patches of the cortex to selectively control just the right neurons at the right times to do the right things.

3 questions for Mriganka Sur: The basic research origin of the first approved drug to treat Rett syndrome

March 10, 2023
On March 10 the FDA approved Trofinetide, a drug based on the protein IGF-1, as the first drug available to treat Rett syndrome. The original research showing that IGF-1 could treat Rett syndrome was published by MIT in 2009.

Astrocyte cells critical for learning skilled movements

March 10, 2023
Research Findings
When astrocyte function is disrupted, neurons in the brain’s motor cortex struggle to execute and refine motion, a new study in mice shows.

Immune & Inflamed

March 1, 2023
Research Feature
Neuroscientists are finding that immune system activity within the brain and the body has important impacts on mental health and behavior

Picower Fellows discuss the social context of their science

February 14, 2023
Picower People
Young neuroscientists contributed their perspectives as the MIT Museum works to create a potential ‘Center for Neuroscience & Society’

Sparse, small, but diverse neural connections help make perception reliable, efficient

February 2, 2023
Research Findings
First detailed mapping and modeling of thalamus inputs onto visual cortex neurons show brain leverages “wisdom of the crowd” to process sensory information

Researchers map brain cell changes in Alzheimer’s disease

February 2, 2023
Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue

How Huntington’s disease affects different neurons

January 20, 2023
Research Findings
A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement

Self-assembling proteins can store cellular “memories”

January 10, 2023
Research Findings
Using these engineered proteins, researchers can record histories that reveal when certain genes are activated or how cells respond to a drug.

New technologies revealing cross-cutting breakdowns in Alzheimer’s disease

January 2, 2023
Research Findings
‘Single-cell profiling’ is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways

Holding information in mind may mean storing it among synapses

December 29, 2022
Research Findings
Comparing models of working memory with real-world data, MIT researchers found that information resides not in persistent neural activity, but in the pattern of their connections