A new MIT study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways

Under propofol general anesthesia, sensory input still reaches the brain, but signals do not spread. Results suggest consciousness requires cortical regions to all be “on the same page.”

The Krieg Cortical Kudos Discoverer Award recognizes Nedivi’s ongoing work to understand molecular and cellular mechanisms that enable the brain to adapt to experience

Picower Institute-based collaboration will study mechanisms that might enable peripheral immune cells to deliver a potentially therapeutic molecule to the brain.

Seed projects, posters represent a wide range of labs working on technologies, therapeutic strategies, and fundamental research to advance understanding of age-related neurodegenerative disease

An advanced closed-loop anesthesia delivery system that monitors brain state to tailor propofol dose and achieve exactly the desired level of unconsciousness could reduce post-op side effects

Society for Neuroscience Award recognizes Professor Mark Bear’s synaptic plasticity research, its translation to potential amblyopia and autism treatments, and his career of mentorship.

A flexible new tool both monitors and manipulates neural activity in the brains of large animals.

Five MIT faculty, along with seven additional affiliates, are honored for outstanding contributions to medical research.

By analyzing epigenomic and gene expression changes that occur in Alzheimer’s disease, researchers identify cellular pathways that could become new drug targets

In C. elegans worms, a single neuron named HSN uses multiple chemicals and connections to orchestrate egg-laying and locomotion over the course of several minutes

Scientists have invested decades in piecing together how our vision is so good at recognizing what’s familiar. A new study overcomes an apparent discrepancy in data to reveal a new insight into how it works.