A security guard views a bank of eight monitors on his desk. The perspective of the image is from behind the security guard so that the various parts of a building's interior is visible on the monitors.
October 20, 2025
Like radar, a brain wave sweeps a cortical region to read out information held in working memory
Six panels show circular arrangements of each individual cell type in a miBrain culture, stained in cyan. The cell types are Pericytes, Astrocytes, Endothelial Cells, Neurons, Oligodendroglia, and Microglia
October 17, 2025
MIT invents human brain model with six major cell types to enable personalized disease research, drug discovery
An array of six panels shows different views of a long, thin, spiny structure that closely resembles a bumpy twig. Each is stained bright green and the degree of bumpiness varies along each one.
October 16, 2025
Study finds circular RNA helps drive brain development
Two stacked electron microscope images show a synapse. Above a small, river-like gap is a dark T shape among many tiny bubble-like circles. In the bottom image the T shape is much bigger than in the upper image.
October 14, 2025
Neural activity helps circuit connections mature into optimal signal transmitters
The almond shape of the amygdala is composed of cells stained red (on the left) and green (on the right).
September 29, 2025
Many Mechanisms of Mood

New award funds study of a remarkable example of neural regeneration

July 1, 2023
New Research
A three-year fellowship will support Brady Weissbourd’s research on how the C. hemisphaerica jellyfish survives and thrives by constantly making new neurons.

Petite & Profound

June 22, 2023
Research Feature
Why studying simple organisms—none larger than the palm of your hand—is so integral to understanding nervous system health, disease and evolution.

Picower postdoc earns Burroughs Wellcome Fund award

June 13, 2023
Picower People
‘Career Award at the Scientific Interface’ recognizes Rebecca Pinals’ research to create a nanosensor-integrated brain-on-a-chip model of Alzheimer’s disease.

Without key extracellular protein, neuronal axons break and synaptic connections fall apart

June 12, 2023
Research Findings
MIT scientists find evidence that a protein common to flies and people is essential for supporting the structure of axons that neurons project to make circuit connections. When those break down, the connections follow suit.

Mind to molecules: Does brain’s electrical encoding of information ‘tune’ sub-cellular structure?

May 22, 2023
Research Findings
Brain waves carry information. A new “Cytoelectric Coupling” hypothesis posits that fluctuating electric fields optimize brain network efficiency and stability by shaping the brain’s molecular infrastructure.

40 Hz vibrations reduce Alzheimer’s pathology, symptoms in mouse models

May 18, 2023
Research Findings
Tactile stimulation improved motor performance, reduced phosphorylated tau, preserved neurons and synapses and reduced DNA damage, a new study shows

From labs to the streets, experts work to defuse childhood threats to mental health

May 18, 2023
Picower Events
Symposium speakers describe numerous ways to promote prevention, resilience, healing and wellness after early life stresses

From molecular to whole-brain scale in a simple animal, study reveals serotonin’s effects

May 15, 2023
Research Findings
With full genetic control and visibility into neural activity and behavior, MIT scientists map out chemical’s role in behavior

Neuroscientists identify cells especially vulnerable to Alzheimer’s

April 19, 2023
Research Findings
Neurons that form part of a memory circuit are among the first brain cells to show signs of neurodegeneration in Alzheimer’s disease.

A new peptide may hold potential as an Alzheimer’s treatment

April 12, 2023
Research Findings
The peptide blocks a hyperactive brain enzyme that contributes to the neurodegeneration seen in Alzheimer’s and other diseases.

Fluid flow in the brain can be manipulated by sensory stimulation

April 10, 2023
Research Findings
Blood flow induced by visual stimulation drives the flow of cerebrospinal fluid

Studying consciousness without affecting it

April 6, 2023
Research Findings
A new study tests an alternative to external stimulation for measuring when subjects lose and regain responsiveness during sedation and anesthesia.