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Astrocyte cells critical for learning skilled movements

March 10, 2023
Research Findings
When astrocyte function is disrupted, neurons in the brain’s motor cortex struggle to execute and refine motion, a new study in mice shows.

3 questions for Mriganka Sur: The basic research origin of the first approved drug to treat Rett syndrome

March 10, 2023
On March 10 the FDA approved Trofinetide, a drug based on the protein IGF-1, as the first drug available to treat Rett syndrome. The original research showing that IGF-1 could treat Rett syndrome was published by MIT in 2009.

Immune & Inflamed

March 1, 2023
Research Feature
Neuroscientists are finding that immune system activity within the brain and the body has important impacts on mental health and behavior

Picower Fellows discuss the social context of their science

February 14, 2023
Picower People
Young neuroscientists contributed their perspectives as the MIT Museum works to create a potential ‘Center for Neuroscience & Society’

Sparse, small, but diverse neural connections help make perception reliable, efficient

February 2, 2023
Research Findings
First detailed mapping and modeling of thalamus inputs onto visual cortex neurons show brain leverages “wisdom of the crowd” to process sensory information

Researchers map brain cell changes in Alzheimer’s disease

February 2, 2023
Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue

How Huntington’s disease affects different neurons

January 20, 2023
Research Findings
A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement

Self-assembling proteins can store cellular “memories”

January 10, 2023
Research Findings
Using these engineered proteins, researchers can record histories that reveal when certain genes are activated or how cells respond to a drug.

New technologies revealing cross-cutting breakdowns in Alzheimer’s disease

January 2, 2023
Research Findings
‘Single-cell profiling’ is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways

Holding information in mind may mean storing it among synapses

December 29, 2022
Research Findings
Comparing models of working memory with real-world data, MIT researchers found that information resides not in persistent neural activity, but in the pattern of their connections

Small studies of 40Hz sensory stimulation confirm safety, suggest Alzheimer’s benefits

December 1, 2022
Research Findings
MIT researchers report early stage clinical study results of tests with non-invasive 40Hz light and sound treatment

Research offers insights into mechanisms underlying bipolar mania, sleep homeostasis

November 23, 2022
Recent Events
At a press conference at Society for Neuroscience Annual Meeting, young Picower scientist Takato Honda presented findings of key neurons involved in the neuropsychiatric disorder and sleep homeostasis