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Engrams: mapping and manipulating memories

… using techniques to label and then take control of engram cells, the lab has been able to map engrams and manipulate … foot in an enclosure. Typically when mice return to that place, they freeze. The researchers discovered that if they … the hippocampal engram of a previously experienced place while giving the mouse a little shock somewhere else. …

Silent Engrams: Distinctions between memory storage and recall

… shock to the foot in a particular cage) they labeled the cells involved (known collectively as the memory “ engram ”). They saw that the cells exhibited considerable strengthening of their … memory when placed in the cage where the little shock took place. Was the problem a failure of storage, or of recall? …

Antidepressant restores youthful flexibility to aging inhibitory neurons in mice

August 20, 2018
… fresh evidence that the decline in the capacity of brain cells to change, called “plasticity,” rather than a decline … restore a significant degree of lost plasticity to the cells by giving treating mice with the commonly used … Foundation supported the research. 45 38 27 Small Image in Place of Hero Off List on Aging Brain Initiative Page On List …

New findings reveal how neurons build and maintain their capacity to communicate

July 20, 2022
… to communicate July 20, 2022 Research Findings Nerve cells regulate and routinely refresh the collection of … Nociception https://elifesciences.org/articles/78648 Nerve cells regulate and routinely refresh the collection of … support for the research. 43 26 27 20 Small Image in Place of Hero On List on Aging Brain Initiative Page Off List …

Technology makes tissues elastic and lasting for easier imaging

May 18, 2020
… a solution that is much more literal. To make imaging cells and molecules in brain and other large tissues easier … provides scientists a very fast way to fluorescently label cells, proteins, genetic material and other molecules within … Foundation Technology Award. 40 222 31 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …
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