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Innovations giving neuroscientists exciting new ways to gain insights, symposium speakers say

October 25, 2018

… cortex, an important area of scientific interest because cells there receive input to those spines from the thalamus. … brain, after all, can have scores of different types of cells, each playing a diversity of roles. His goal is to help … is a golden age.” 40 39 222 220 31 32 Small Image in Place of Hero Off List on news page On …

Protein has unique effects in neural connections related to information processing

October 09, 2018

… how well the connections, or synapses, between our brain cells transmit signals. A new study by researchers at MIT’s … how well the connections, or synapses, between our brain cells transmit signals. A new study by researchers at MIT’s … Seed Grant funded the research. 15 27 Small Image in Place of Hero Off List on news page On …

How could Covid-19 and the body’s immune response affect the brain?

April 21, 2020

… molecules, called cytokines, emitted by immune system cells, those interactions can directly affect neural … given a particular maternal microbiome composition, immune cells in pregnant mice expressed elevated levels of the … effects of coronavirus infection. 2 443 3 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

Consciousness

June 12, 2024

Engrams: mapping and manipulating memories

… using techniques to label and then take control of engram cells, the lab has been able to map engrams and manipulate … foot in an enclosure. Typically when mice return to that place, they freeze. The researchers discovered that if they … the hippocampal engram of a previously experienced place while giving the mouse a little shock somewhere else. …

Silent Engrams: Distinctions between memory storage and recall

… shock to the foot in a particular cage) they labeled the cells involved (known collectively as the memory “ engram ”). They saw that the cells exhibited considerable strengthening of their … memory when placed in the cage where the little shock took place. Was the problem a failure of storage, or of recall? …

With sophisticated tools in a simple model, scientists aim to learn how serotonin modulates behavior

February 20, 2020

… New NIH grant funds study that will span receptors, cells, the whole brain and behavior Neuromodulators … indicates neural activity while red mCherry labels all cells. Focus on feeding “By taking advantage of a … of the serotonergic system.” 41 14 31 278 Small Image in Place of Hero On List on Aging Brain Initiative Page Off List …

Study suggests new molecular strategy for treating fragile X syndrome

February 20, 2025

… of Health funded the study. 38 3 27 Small Image in Place of Hero On List on Aging Brain Initiative Page Off List …

Antidepressant restores youthful flexibility to aging inhibitory neurons in mice

August 20, 2018

… fresh evidence that the decline in the capacity of brain cells to change, called “plasticity,” rather than a decline … restore a significant degree of lost plasticity to the cells by giving treating mice with the commonly used … Foundation supported the research. 45 38 27 Small Image in Place of Hero Off List on Aging Brain Initiative Page On List …

Circuit model may explain how deep brain stimulation treats Parkinson’s disease symptoms

May 16, 2022

… striatum from excessive excitement among striatum-dwelling cells called medium spiny neurons (MSNs). Schematic … that under healthy conditions, with adequate dopamine, cells in the striatum called fast-spiking interneurons (FSIs) … for the research. 39 221 241 220 279 Small Image in Place of Hero Off List on Aging Brain Initiative Page On List …