August 08, 2017
Blocking a key enzyme may reverse memory loss
… to developing treatments for Alzheimer’s disease. HDAC2 Sp3 treatment epigenetics … by blocking its interaction with a binding partner called Sp3. “This is exciting because for the first time we have … further testing. Those tests revealed that a gene called Sp3 is necessary to recruit HDAC2 to chromatin to enact its …