… It is extremely difficult to investigate what is taking place in vivo at the onset of the disease. iv) The low … and psychiatric diseases in which access to the affected cells and pathogenic sites is limited. So far, we have … Off On Organizer Email bgreeno@mit.edu Small Image in Place of Hero Off …
… single generation, by ‘ES-mouse’ method, where we treat ES cells using three inhibitors to keep their potency and then inject such ES cells into 8-cell-stage embryos. These procedures … Off Off Organizer Email bgreeno@mit.edu Small Image in Place of Hero Off …
… of healthy glial progenitors, oligodendrocyte precursor cells (OPCs), and the consequent generation of new … of neuronal activity on normal oligodendroglial precursor cells, a putative cellular origin for many forms of glioma, … Off Off Organizer Email bgreeno@mit.edu Small Image in Place of Hero Off …
… she made the breakthrough discovery that radial glial cells are neural stem cells. This inspired her to attempt turning also adult mature … Off Off Organizer Email bgreeno@mit.edu Small Image in Place of Hero Off …
… cell types with light, observe activity of thousands of cells in a living brain, and interrogate fine molecular and … Furthermore, we can grow mini brains derived from patient cells to study human-specific disease mechanisms. The Picower … Organizer Email bgreeno@mit.edu Small Image in Place of Hero Off …
… generate human neurons by directly converting non-neural cells like fibroblasts. We use this approach to model aging … Off On Organizer Email bgreeno@mit.edu Small Image in Place of Hero Off …
… brain. Spread involves the uptake of tau into recipient cells and its templating of normal tau in the recipient cell … than 350 published papers cover synaptic plasticity, stem cells, brain evolution, and the biology of Alzheimer’s … Off On Organizer Email bgreeno@mit.edu Small Image in Place of Hero Off …
