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… and the genetically-defined hypothalamic neurons that control these states, as a natural means to direct a mouse’s …

… dynamics in primate prefrontal networks: relevance to cognitive control and schizophrenia 2018-09-06T16:00:00-0400 … in prefrontal networks, potentially helping to explain cognitive deficits in diseases such as schizophrenia that are …

… thermoregulation, fluid/ionic balance, hunger/satiety control and seasonal reproduction. We employ … responsible for cold tolerance and fluid ionic balance control in mammalian hibernators. Our recent work shed light …

… Zoom:   https://mit.zoom.us/j/91469352101 Organization and Control of Hippocampal Circuits   When animals are in an … be largely disengaged from the present setting to enable cognitive mechanisms such as memory consolidation and … during non-locomotor behavior, extending the repertoire of cognitive processes beyond the classical “off-line” …

… for the trafficking of the glutamate receptors, but also control the gating of the receptor channel. The other family … synaptic proteins in glutamate receptor trafficking TARPs control of AMPA receptor gating Activity dependent …

… turn within a specific brain region associated with motor control. This early, local difference in neural activity …

… brain levels of KYNA associate with psychotic features and cognitive dysfunctions. Studies in rodents demonstrate that … and dopaminergic neurotransmission to induce psychosis and cognitive dysfunction.   We have now investigated the status … aminotransferases (KAT) II significantly reduces KYNA in control rats, recent data from our lab reveal though that …

… particular focus on brain networks important to memory and cognitive control. Current projects include using novel approaches …