Six portraits across two rows: Joe Coughlin, Giovanni Traverso, Pattie Maes across the top and Bin Zhang, Laura Kiessling and Ed Boyden along the bottom.
June 9, 2025
Aging Brain Initiative seed grants fund five new projects to address neurodegenerative disease
Against a dark blue background we see two sine waves shifted out of phase with eachother
May 12, 2025
Different anesthetics, same result: unconsciousness by shifting brainwave phase
Neurons glow green against a black background in a section of a mouse brain. A few red specks can be seen. An inset magnifies one of these cells that has red and green staining.
April 28, 2025
Dopamine signals when a fear can be forgotten
A 2 by 2 array of panels that each show a hairpin-like shape of blue stained cells. The left column is laberled "Ambient light/sound." The right column is labeled "40Hz Stimulation." The panels in the 40Hz column show more yellow arrows pointing white blotches than the panels in the ambient column.
April 24, 2025
In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity
Emery Brown sits behind his desk in his MIT office. A teddy bear rests nestled among some books on a shelf behind him, just over his right shoulder.
April 21, 2025
In kids, EEG monitoring of consciousness safely reduces anesthetic use

Brown wins share of 2022 Gruber Neuroscience Prize

May 17, 2022
Picower People
Emery N. Brown and three other scientists recognized for advancing statistical, theoretical analyses of neuroscience data

Circuit model may explain how deep brain stimulation treats Parkinson’s disease symptoms

May 16, 2022
Research Findings
Stimulation of subthalamic nucleus interrupts a cycle of runaway beta-frequency rhythms and restores ability of interneurons to regulate rhythms in the brain’s striatum, improving movement, study suggests

Anesthetic drastically diverts the travels of brain waves

April 27, 2022
Research Findings
Under propofol general anesthesia very slow frequency traveling waves transform and dominate, redirecting and disrupting the higher frequency traveling waves associated with conscious function

Circuit that focuses attention brings in wide array of inputs

April 21, 2022
Research Findings
With a comprehensive map of the wiring, researchers can now discern what information flows into the circuit to enable a key brain function

Aging Brain Initiative awards fund 5 new ideas to study, fight neurodegeneration

April 20, 2022
New Research
Competitive seed grants launch yearlong investigations of novel hypotheses about potential causes, biomarkers, treatments of Alzheimer’s and ALS.

A single memory is stored across many connected brain regions

April 11, 2022
Research Findings
Innovative brain-wide mapping study shows that “engrams,” the ensembles of neurons encoding a memory, are widely distributed, including among regions not previously realized

Emery Brown earns AIMBE’s highest honor

March 25, 2022
Picower People
Pierre Galletti Award recognizes contributions to neural signal processing, anesthesiology advances

The model remodeler

March 14, 2022
Research Feature
A Picower Institute primer on ‘plasticity,’ the brain’s amazing ability to constantly adapt to and learn from experience

Neurons are fickle. Electric fields are more reliable for information.

March 14, 2022
Research Findings
A new study suggests that electric fields may represent information held in working memory, allowing the brain to overcome “representational drift,” or the inconsistent participation of individual neurons

Mriganka Sur elected to the 2022 class of the AIMBE College of Fellows

February 28, 2022
Picower People
National Institute recognizes innovations and research elucidating neuronal plasticity and computations

A new “atlas” of cells that carry blood to the brain

February 14, 2022
Research Findings
Single-cell gene expression analyses of human cerebrovascular cells can help reveal new drug targets for Huntington’s disease and other neurodegenerative diseases.

Research advances technology of AI assistance for anesthesiologists

February 2, 2022
Research Findings
A new deep learning algorithm trained to optimize doses of propofol to maintain unconsciousness during general anesthesia could augment patient monitoring