To remember Susumu Tonegawa, nearly 200 lab members and alumni, biology and neuroscience colleagues, and other well-wishers gathered with members of his family Oct. 16 in MIT Building 46 and online.

With evidence from human cell cultures, post-mortem brain samples and mice, MIT researchers show that the APOE4 gene variant suppresses molecular signaling needed for oligodendrocytes to myelinate neurons. They also demonstrate a proof-of-concept fix.

In six talks Sept. 25, researchers from across MIT described projects aimed at advancing the understanding of and interventions against neurodegenerative diseases such as Alzheimer’s, Parkinson’s and ALS

Brain disorders are notoriously mysterious. To improve diagnosis and to better measure treatment efficacy, Picower Institute labs are developing objective and minimally invasive indicators of brain health.

Making a decision requires juggling a set of options without getting them confused or losing track of them. A new MIT study shows how ensembles of neurons encode information to maximize clarity throughout the process.

Delivered at just the right time, this type of auditory stimulus can strengthen the flow of cerebrospinal fluid, which clears debris from the brain and keeps it healthy.

A new study reveals insights into populations of neurons affected by Huntington’s disease, schizophrenia, addiction, and other disorders.

The brain's ability to generate quick, nimble volitional thought—and a unified awareness of thought and experience—arises from analog computations carried out by electrical waves, MIT neuroscientists argue in a new review

Neuroscientists have discovered circuits in the prefrontal cortex that can be repurposed to store different types of information.

The new technique could help scientists learn how the entire brain works to generate decisions and emotions.

With the tough job of trying to keep track of what’s going on in front of it, the brain relies not only on what it sees, but also a comparison with what it just saw. A new study in mice pinpoints the circuit that provides that service.

Observations conflict about whether hormone replacement therapy increases or decreases Alzheimer’s likelihood for women. With a new award from the Massachusetts Life Sciences Center, MIT researchers will investigate the underlying molecular mechanisms aff