Three views of an organoid cell culture show the constiuent cells of the vaguely round, tangled mass of cells.  In the different views the cells are highlighted in different colors such as magenta and green.
April 14, 2026
Rett syndrome study highlights potential for personalized treatments
A video screenshot shows a grayscale worm twisting its body around in a loop to change direction
April 10, 2026
With navigating nematodes, scientists map out how brains implement behaviors
A member of a surgical staff holds a mask on the face of an unconscious patient in an operating room
March 17, 2026
Three anesthesia drugs all have the same effect in the brain, MIT researchers find
Li-Huei Tsai stands at a podium embossed with an MIT logo. In the foreground is an attentive audience. In the background is the Picower Institute logo
March 11, 2026
After 16+ years leading Picower Institute, Li-Huei Tsai will sharpen focus on research, teaching
Two panels show blue cells surrounded by thin green outlines. The outlines are much more consistent and prevalent in the image on the left, which is labeled as the wild type, than on the right which is labeled Rett syndrome.
February 25, 2026
In Rett syndrome, leaky brain blood vessels traced to microRNA

Study finds tracking brain waves could reduce post-op complications

July 17, 2023
Research Findings
Distinctive EEG patterns indicate when a patient’s state of unconsciousness under general anesthesia is more profound than necessary.

Brain networks encoding memory come together via electric fields, study finds

July 10, 2023
Research Findings
New research provides evidence that electric fields shared among neurons via “ephaptic coupling” provide the coordination necessary to assemble the multi-region neural ensembles (“engrams”) that represent remembered information.

New award funds study of a remarkable example of neural regeneration

July 1, 2023
New Research
A three-year fellowship will support Brady Weissbourd’s research on how the C. hemisphaerica jellyfish survives and thrives by constantly making new neurons.

Petite & Profound

June 22, 2023
Research Feature
Why studying simple organisms—none larger than the palm of your hand—is so integral to understanding nervous system health, disease and evolution.

Picower postdoc earns Burroughs Wellcome Fund award

June 13, 2023
Picower People
‘Career Award at the Scientific Interface’ recognizes Rebecca Pinals’ research to create a nanosensor-integrated brain-on-a-chip model of Alzheimer’s disease.

Without key extracellular protein, neuronal axons break and synaptic connections fall apart

June 12, 2023
Research Findings
MIT scientists find evidence that a protein common to flies and people is essential for supporting the structure of axons that neurons project to make circuit connections. When those break down, the connections follow suit.

Mind to molecules: Does brain’s electrical encoding of information ‘tune’ sub-cellular structure?

May 22, 2023
Research Findings
Brain waves carry information. A new “Cytoelectric Coupling” hypothesis posits that fluctuating electric fields optimize brain network efficiency and stability by shaping the brain’s molecular infrastructure.

From labs to the streets, experts work to defuse childhood threats to mental health

May 18, 2023
Picower Events
Symposium speakers describe numerous ways to promote prevention, resilience, healing and wellness after early life stresses

40 Hz vibrations reduce Alzheimer’s pathology, symptoms in mouse models

May 18, 2023
Research Findings
Tactile stimulation improved motor performance, reduced phosphorylated tau, preserved neurons and synapses and reduced DNA damage, a new study shows

From molecular to whole-brain scale in a simple animal, study reveals serotonin’s effects

May 15, 2023
Research Findings
With full genetic control and visibility into neural activity and behavior, MIT scientists map out chemical’s role in behavior

Neuroscientists identify cells especially vulnerable to Alzheimer’s

April 19, 2023
Research Findings
Neurons that form part of a memory circuit are among the first brain cells to show signs of neurodegeneration in Alzheimer’s disease.

A new peptide may hold potential as an Alzheimer’s treatment

April 12, 2023
Research Findings
The peptide blocks a hyperactive brain enzyme that contributes to the neurodegeneration seen in Alzheimer’s and other diseases.