… moment.” The researchers designed their tool to respond to calcium, because neurons experience an flux of calcium ions every time they fire an electrical impulse. However, the neurons are only labeled if this calcium flux occurs while the cell is also exposed to a beam …
… glutamate release, called active zones (AZs), took in more calcium ions in phasic neurons than tonic ones. A … hypothesizes that this difference could allow for more calcium ions to crowd into the phasic active zones, perhaps … scientists had also found that phasic neurons express a calcium-ion buffering gene >30-fold more than tonic ones. …
… caused non-neural “glial” cells to retain too much calcium. By 2019 they found out how that led to seizures. The excess of calcium overactivated a protein called calcineurin. That …