… the hippocampus, a region known for memory. That indicated LTD was a plasticity rule throughout the brain. In 2004 in Neuron, Bear’s lab, which had moved to MIT, showed that LTD of V1 neurons serving the deprived eye helped explain the … cortex synapses serving the deprived eye did not undergo LTD. MD models a common visual disorder called amblyopia in …
… showed that NMDA receptors trigger long ‐ term depression (LTD) as well as long ‐ term potentiation (LTP) in the cortex, that the properties of LTD and LTP are themselves 'metaplastic' and depend on the … of the visual cortex. His lab’s demonstration of LTD in the hippocampus was paradigm ‐ shifting, opening the …
… Institute of Technology Research Areas mGluR5 , LTD , LTP , monocular deprivation , habituation , … a phenomenon called homosynaptic long-term depression (LTD). LTD is the functional inverse of long-term synaptic …